The US Food and Drug Administration (FDA) has declined to approve Applied Therapeutics’ govorestat for classic galactosemia, prolonging the wait for the first marketed treatment for the genetic ...
The CDR1α and CDR3α loops of the iNKT TCR and the galactose headgroup of the α-GalCer analogues generally adopted very similar positions within all the ternary complexes and subtle changes in the ...
Originally based on molecular addon from pyroevil. https://github.com/Pyroevil/Blender-Molecular-Script and the efforts of PavelBlend and Scorpion81 for maintaining ...
TamGen offers a new approach to drug discovery by applying the principles of generative AI to molecular design. Unlike traditional methods, which depend on systematically screening known compounds—a ...
The deadline for the FDA’s verdict is Nov. 28. With around 3,000 diagnosed cases in the U.S., galactosemia is a rare, genetic and metabolic disorder characterized by the impaired or complete lack of ...
Researchers at Karolinska Institutet have found a molecule that can both help the intestines to heal after damage and suppress tumor growth in colorectal cancer. The discovery could lead to new ...
First molecule identified that promotes gut healing while inhibiting tumour progression. ScienceDaily . Retrieved December 17, 2024 from www.sciencedaily.com / releases / 2024 / 11 / 241120121726.htm ...
Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, Aichi 465-8603, Japan Exploratory Research Center on Life and Living Systems (ExCELLS), National Institutes of Natural ...
Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...
Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...