This valuable study addresses potential roles of the master regulator of X chromosome inactivation, the Xist long non-coding RNA, in autosomal gene regulation. Using data from mouse cells, the authors ...
In a recent paper published in Cancer Discovery, Keio University's Sara Horie and her colleagues conducted an in-depth analysis of cancer driver alterations using genomic data from Japanese and ...
For example, Huntington’s disease (HD), the first expansion disorder discovered, occurs when a cysteine-arginine-guanine (CAG) trinucleotide in the HTT gene swells to 40 or more repeats. Such ...