The present study quantifies the impact of the presence of tophi and frequency of acute gout attacks on health-related quality of life (HRQOL), productivity, and healthcare resource utilization.

Patients with tophi also had significantly greater impairment of work productivity and activity. Tophaceous gout was associated with greater absenteeism and overall work impairment than both the ...

Tophaceous gout is a severe form of gout. It results when uric acid crystals form, leading to growths called tophi around the ...

Gout in the patients of Group 2, however, was more advanced. Tophi were not only much more common in this group (9 of 10 as opposed to 11 of 20 in Group 1) but also greater in size and number.

Tophi are a symptom of gout. They are large, hardened masses of uric acid crystals within and around the joints. These masses can cause pain, joint deformity, and limited range of motion.

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

and chronic gouty arthritis with multiple gouty tophi. He had also had hyperuricemia for many years, with uric acid concentrations of up to 9.8 mg/dl. Initial treatment with febuxostat 80 mg bid ...

Sudden and severe pain in the joints, particularly in the big toe, is a common sign of gout, which is caused by high uric acid levels. Swelling and Inflammation: Joints may become swollen, red, and ...

with gout. Mean patient age was 56.3 years, and mean disease duration was 9.3 years. In all, 52.4% of patients had joint pain, 22.8% had swelling, 32.5% had reduced mobility and 36.9% had tophi.