Tophi are firm, painless yellow lesions that form in and around the joints in people with advanced gout. They have a uric acid (monosodium urate) core, and the skin that covers them can become ...

Gout patients frequently have a number of comorbidities, including obesity, hypertension, high serum lipid and cholesterol levels, kidney disease, diabetes, and cardiovascular disease. [2,7,19 ...

Tophaceous disease occurs early in the course of gout in approximately 15% people. The presence of tophi is strongly associated with features of chronic joint inflammation, pain and activity ...

A young adult patient with gout was incidentally found to have a large mass on the right lumbar spine and sacrum during an ...

The following is a summary of “Non-adherence to urate lowering therapy in gout after 5 years is related to poor ...

Severe gout was defined by the presence of 5 or more tophi. The mechanisms of generalized neuropathy remain unclear and likely involve multiple factors. Patients with gout and neuropathic symptoms ...

Untreated gout places a substantial burden on the global health system, as chronic gout causes tophi formation, chronic joint ...

Nutritional deficiencies don't cause gout, but people with gout often have them. Research indicates that adding supplements such as methylsulfonylmethane (MSM), folic acid, and vitamins C, D, and B12 ...

Significant differences in gout duration, number of urate arthropathies, serum urate (SU) levels, tophi, blood urea nitrogen (BUN), serum creatinine (sCr), and estimated glomerular filtration rate ...

Gout affects around 9 million Americans, and around 50% of those with gout will have their first attacks begin in the big toe. The severity of gout will depend on the individual, but, on average ...

Left untreated, gout in the elbow can lead to permanent joint damage and tophi—painful bumps where uric acid crystals have built up around the joint. Taking your medications as prescribed and ...