The lineshape of a single histidine resonance was fit as a function ... with the preorganization of one or more elements of secondary structure in the unfolded protein.
The τ-nitrogen of D2 histidine 189 is the hydrogen bond donor to the tyrosine radical YD of photosystem ... Yachandra, V.; Klein, M.P. “Oxidation States and Structure of the Manganese Cluster in the ...
However, how the substrate CtA, a 90-residue polypeptide, is recognized by PCAT1 remained elusive. To address this question, we determined the structure of the PCAT1-CtA complex by electron ...
Structure-guided mutagenesis revealed that AcrVA4 dimerization is not required for inhibition of Cas12a in vitro and provided no advantage to bacteriophage targeted by Cas12a in vivo. Finally, we ...