Statins lower plasma cholesterol by upregulating LDL receptor gene expression and are consequently relatively ineffective in homozygous familial hypercholesterolemia (HoFH). The standard treatment ...

Homozygous or compound heterozygous insulin receptor mutations can cause the Leprechaun syndrome, where there is marked intrauterine growth retardation in addition to severe insulin resistance 19,20.

The rate of the postapheresis rebound in LDL depends upon its production rate (zero order) and removal rate (first order), being slowest to plateau in homozygous FH, intermediate in heterozygous ...

September/2592024/piv.jpg" width="1200" height="675" /> CBSE 2024-25 Competency-Based Questions With Answers: The Central Board Of Secondary Education has made available the competency-based questions ...

The prevalence of type 2 diabetes, along with related conditions, such as metabolic syndrome and obesity, has increased ...

This is an important piece of work that sheds light on our understanding of early lung development. There is solid evidence that there is a key new role for Svep1, which may be acting via FGF9. A more ...

People need to understand that inherited heart diseases are genetically determined. They are transmitted from parents to ...

Note: Read coverage should be at least 20x to tell the difference between heterozygous and homozygous kmers reliably. We assume that the kmer counts are in the KFF format. Any kmer counter supporting ...

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