Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition that can lead to atrial fibrillation, heart failure, and sudden cardiac death in many individuals but mild clinical impact in others. The ...

Left ventricular hypertrophy: clinical findings and ECG diagnosis. In: UpToDate, Mirvis DM(Eds), Wolters Kluwer American Heart Association. Dilated cardiomyopathy. American Heart Association.

Hypertrophic cardiomyopathy (HCM) is an uncommon disease with significant consequences. Since the 1950s, major strides in understanding its etiology and pathogenesis have led to improved ...

Jagdish Butany, MBBS, MS, FRCPC, Department of Pathology, Toronto General Hospital, University Health Network; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto ...

We review this progress, in the context of human pathology, and consider the future directions that the field will need to take towards new therapies. The mitochondrial genome The OXPHOS system is ...

Thuy Tran’s research group has been awarded 8 million SEK over three years from the Erling-Persson Foundation to develop a precision-focused, theranostic method that integrates both diagnostics and ...

We show here that absence of the melanocortin-4 receptor (MC4R) in mice causes dilated cardiomyopathy, characterized by reduced contractility and increased left ventricular diameter. This ...