Targeting two particular proteins, called H1.2 and PARP1, may lessen the severity of amyotrophic lateral sclerosis (ALS) linked to mutations in the FUS gene, a study shows. Researchers found that a ...

Human papillomavirus (HPV) and hyperactivated YAP1 form a YAP1-HPV oncogenic alliance to drive the malignant transformation ...

My daughter, Sara, is beginning her freshman year at a university a couple hours from us, and last Saturday was her day to move into the dorms. I had planned to help her move, so weeks ago I lined up ...

Figure 1. M1 and M2 macrophage polarization: Upon inflammatory (LPS, INFγ, TNFα) stimuli, macrophages are polarized into inflammatory M1 phenotype by activating NF-kB inflammatory pathway, ...

Insulin Like Growth Factor Binding Protein (IGFBP) is a transport protein for insulin-like growth factors (IGFs). It is transcribed into seven genes (IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, IGFBP6 and ...

1 Department of Oncology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China 2 Institute of Precision Medicine, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, ...

Approximately 98% of IGF-1 is always bound to one of six binding proteins (IGF-BP). IGFBP-3, the most abundant protein, accounts for 80% of all IGF binding. IGF-1 binds to IGFBP-3 in a 1:1 molar ratio ...

The role of cellular senescence in human heart failure (HF) remains unclear. The senescence‐associated secretory phenotype (SASP) is composed of proteins released by senescent cells. We assessed the ...

胰岛素样生长因子结合蛋白（英语：Insulin-like growth factor-binding protein，缩写IGFBP）是胰岛素样生长因子1（IGF-1）的载体蛋白[2] 。 Quick Facts Insulin-like growth factor binding protein, 鉴定 ... Insulin-like growth factor ...