面对这一关键问题，针对药物的胞内靶点实现精准递送显得尤为关键。内质网，作为细胞内的蛋白质合成与修饰中心，在化疗免疫治疗的策略中占据核心位置。特别是在结直肠癌治疗中，当内质网受到扰动时，会激活一系列信号通路，触发免疫原性细胞死亡（ICD）的发生，进而激 ...

In a study published in Nature Nanotechnology, researchers discovered that cuproptosis may serve as a new target for ...

Learn about the revolutionary neoantigen therapies and mRNA vaccines transforming cancer treatment by harnessing the body's ...

Researchers from Bulgaria conduct an analysis of the potential for therapeutic vaccines in by comparing testing results for ...

Due to the remarkable success of the Research Topic 'New Insights in Veterinary Cancer Immunology' and the rapidly evolving subject area, we are pleased to launch Volume II for this topic. The tumour ...

In vivo, using the subcutaneous MB49 bladder cancer model, HSV5-15 virus expressing both the cytokine and TLR agonist ...

Such gene regulation systems, combining safe small molecules with non-immunogenic RNA switches, would be significantly safer to use in clinical applications as well as in biological studies. The small ...

Although the role of innate immune sensing pathways is well-studied in the pathogenesis of malignancies, whether they ...

Vaxcyte's stock surges on promising vaccine data, offering potential upside despite competition. Learn more on PCVX here.

(2022) Localized ablative immunotherapy drives de novo CD8+ T-cell responses to poorly immunogenic tumors. J. Immunother. Cancer. 10, e004973. PMID: 36253002. Zhao X, Kolawole EM, Chan W, Feng Y, Yang ...