Nurix Therapeutics, Inc. (Nasdaq: NRIX), a clinical stage biopharmaceutical company developing targeted protein modulation drugs designed to treat patients with cancer and inflammatory diseases, today ...

Cells producing interleukin-6 (IL-6) and the actions of IL-6 in the body. Ig = immunoglobulin, CRP = C-reactive protein, SAA = serum amyloid A protein. Reprinted, with permission, from reference 21.

Type 2 diabetes (T2D) and obesity (OB) are associated with chronic low-grade inflammation and increased fracture risk. In vitro studies showed that inflammation induces bone erosion and inhibits bone ...

Summary: Tocilizumab is a novel monoclonal antibody that competitively inhibits the binding of interleukin-6 (IL-6) to its receptor (IL-6R). Inhibiting the entire receptor complex prevents IL-6 ...

A daily dose of vitamin B3 reduced inflammation in the lungs of patients with COPD, Danish researchers report. "This is ...

GS-6791 is a selective, orally bioavailable degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), which is being developed in collaboration with Gilead Sciences for the potential ...

The study met its primary and secondary endpoints, demonstrating that treatment with low-dose interleukin-2 is safe ... on Day 148 was 1.401 in the LD IL-2 q4wks group, 1.976 in the LD IL-2 ...

Amongst these interleukin 12 (IL12), through its capacity to promote T helper type 1 (Th1) responses, emerged as a pivotal player in the development and perpetuation of colitis. 1 Genetic deletion or ...