"Better understanding of JAK signaling in different parts of the body not only helps us discover new things about biology but also gives us a glimpse into how JAK medicines might be used in the ...

Inflammation is limited when the enzyme signaling pathways are interrupted, which can help some autoimmune diseases.In this ...

stress and inflammation from high-fat diets further disrupt leptin signaling within proopiomelanocortin (POMC) neurons. This stress inhibits the JAK/STAT pathway, which is essential for leptin's ...

JAK inhibitors are a class of medications that work by blocking Janus kinases (JAKs), enzymes that are involved in the signaling pathways of various cytokines and growth factors. JAK inhibitors offer ...