The most well-known adaptation was the 2002 film "Scooby-Doo," which starred Freddie Prinze Jr., Sarah Michelle Gellar, Matthew Lillard, and Linda Cardellini, with Neil Fanning voicing Scooby.

Linda Cardellini chats with ET at a screening of ... There's a new murder for Sam and Dean to solve, this time with the help of Scooby, Shaggy, Fred, Daphne and Velma!

to cancel a planned sequel. Sarah Michelle Gellar, Freddie Prinze Jr., Linda Cardellini and Matthew Lillard in Scooby-Doo 2: Monsters Unleashed (2004) Lillard explained, “I thought I’d be No.

Sometimes Hollywood careers take unexpected turns.

After 20 years, Matthew Lillard has come back from the critical and box office fizzle of Scooby-Doo 2: Monsters Unleashed ... Freddie Prinze Jr. as Fred Jones and Linda Cardellini as Velma Dinkley.