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The EMBO Journal
13 小时
New players and targets in mannose 6-phosphate-dependent lysosomal sorting
Amidst the wide variety of glycan modifications that are carried out in the Golgi apparatus, the addition of mannose 6-phosphate (M6P) to the N-linked glycans of lysosome-resident hydrolase enzymes ...
GEN
1 小时
Inceptor Binds Excess Insulin and Directs It Toward Degradation
Diabetes drug development gets an advance in study that shows Inceptor binds excess insulin within the beta cell and directs it towards degradation.
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