The Lysosome This small particle acts as the digestive tract of the living cell. Its enzymes dissolve the substances ingested by the cell and under certain circumstances can dissolve the cell itself ...

Now, a sweeping study published October 9 in Immunity unveils a mechanistic link between the two. Scientists led by Mikael Simons of the German Center for Neurodegenerative Diseases in Munich report ...

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Arginine methylation acts as a signal for intracellular proteins to be degraded in lysosomes. We developed methylarginine targeting chimera (MrTAC), a chemical tool that induces proximity with ...

THE recent enthusiasm for organ transplantation has stimulated increased investigation into the problems of organ storage. In particular, the kidney is being extensively studied because of the ...

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Department of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China ...

This handbook contains a comprehensive collection of protocols to streamline imaging workflows and ensure reproducible ...