Immune checkpoint blockade (ICB) therapies can be very effective against some cancers by helping the immune system recognize cancer cells that are masquerading as healthy cells. T cells are built ...

A heterogeneous lung tumor, with different subpopulations of cells depicted in red and and blue. After treatment with a checkpoint blockade, T cells (white) attack some populations (blue) but not ...

6Moores Cancer Center, University of California San Diego, La Jolla, California. 7The Laboratory of Immunology, Moores Cancer Center and Department of Medicine, University of California San Diego, La ...

1UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania. 2Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Patients with gastric cancer peritoneal metastasis (GCPM) have a poor prognosis and respond poorly to conventional treatments. Recently, immune checkpoint blockade (ICB) has demonstrated favourable ...

These immune checkpoint inhibitors can induce long-lasting responses ... Therefore, finding predictive biomarkers to identify which patients won’t benefit from PD-(L)1 blockade therapy is crucial. In ...

Researchers from the National Defense Medical Center in Taiwan have identified an increased risk of psoriasis in patients with cancer undergoing immune checkpoint inhibitor (ICI) treatments ...

Investigators are trying to determine how a woman got past multiple security checkpoints this week at New York’s JFK International Airport and boarded a plane to Paris, apparently hiding in the ...