These cytokines bind heterodimer receptors to activate three major signaling pathways: mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K), and Janus kinase/signal ...

cancer treatments. The signal that starts the MAPK/ERK pathway is the binding of extracellular mitogen to a cell surface receptor. This allows a Ras protein ...

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...

Researchers at Tel Aviv University found that aneuploid cancer cells are more sensitive to certain anti-cancer drugs, ...

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in ...

smu.edu.cn Objectives To investigate the role of tyrosine kinase Fyn in the development of osteoarthritis (OA ... Fyn inhibitors AZD0530 and PP1 significantly attenuated OA progression by blocking the ...

Two complementary studies from the Faculty of Medical and Health Sciences at Tel Aviv University, in collaboration with the ...

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

Historically, scientists in the division were the first to make the ground-breaking discovery of the mechanism by which the RAS gene – one of the most commonly activated genes in cancer – causes cells ...

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