In this example, it activates an enzymatic cascade of MAP kinases. This results in potent ... activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade that relays ...

Figure 1: Immunocytochemical detection of activation of MAP kinase and PI3 kinase pathways. Figure 3: NT3-induced potentiation of SSCs at NMJ requires activation of PI3 kinase and PLC-γ ...

Two complementary studies from the Faculty of Medical and Health Sciences at Tel Aviv University, in collaboration with the ...

Researchers at Tel Aviv University found that aneuploid cancer cells are more sensitive to certain anti-cancer drugs, ...

and Mitogen-Activated Protein (MAP) kinase pathway genes, which appear to function as modifiers of major RAS drivers rather ...

When blood returns to the heart, it follows a complicated pathway. If you were in the bloodstream, you would follow the steps below one by one. Oxygen-poor blood (shown in blue) flows from the ...

To understand the mechanisms of influenza A viral replication and the host responses, we took the literature-based manual curation approach to construct a comprehensive influenza virus-host respoce ...

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...

One possibility is that in an attempt to overcome the inhibition within the metabolic insulin-signaling pathway, hyperinsulinemia may continue to stimulate the mitogenic insulin-signaling pathway ...

Feng J, Islam A, Bean B, Feng J, Sparapani S, Shrivastava M, Goyal A, Omran, RP, Mallick J, Whiteway M. (2020) Hof1 plays a checkpoint-related role in MMS-induced DNA damage response in Candida ...

RPE-1 cells adapt to aneuploidy in vitro, a process characterized by reduced CIN and inflammation. This study shows that this ...