This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...
It would need to be further validated, for example by in vitro reconstitution of the reaction and monitoring ROS production ... In that previous paper, the laboratory demonstrated that DNA methylation ...
Enzymatic methylation of the C–5 position of cytosine ... The mutational burden of 5–methylcytosine. in Epigenetic Mechanisms of Gene Regulation (eds Riggs, A.D., Martienssen, R.A., and ...
The strongest evidence for a methylation-independent and HDAC-independent mechanism of chromatin condensation by MeCP2 comes from biophysical studies. 58 Purified recombinant MeCP2 was assembled ...
Unusual DNA methylation has been connected to various disease processes, such as cancer, obesity, and other diseases. It also provides the potential for use in agronomic research in identifying ...
Reaction Engines, the British hypersonic aviation pioneer, has crashed into administration after weeks of talks with potential backers failed to result in a rescue deal. Sky News has learnt that ...