The most common adverse effects from methylnaltrexone were abdominal cramps and flatulence, with rates of 30% to 40% and 15% to 20%, respectively. [15] Opioid withdrawal was not reported.

Two novel quaternary opioid antagonists with selectivity for peripheral (i.e., GI) µ-opioid receptors, methylnaltrexone (Figure 1) and alvimopan (Figure 2), have been developed that might prove ...

Astute Analytica has released a comprehensive report titled North American & European Methylnaltrexone Market – Global Industry Trends, Share, Size, Growth, Opportunity and Forecast 2024-2032. This ...