Degenerated CEP, characterized by increased stiffness, decreased permeability, and reduced water content, impairs substance transport and mechanical response within the IVD, ultimately leading to ...

Surgery is typically indicated when six months of conservative therapy have not been successful, if there is a neurologic deficit attributable to the cervical disc disease or when the symptoms ...

Arthritis & Rheumatism. 2006;54(12):3859-3867. Degenerative disc disease is one of today's most common and costly medical conditions. Marked by the gradual erosion of cartilage between the ...

Objective Low back pain (LBP) is a common musculoskeletal disorder, but it is still unclear which individuals develop it. The authors examined the contribution of genetic factors, lumbar disc ...

Degenerative disc disease may be associated with endplate degeneration which may lead to spinal ... A curvature of the spine of at least 10 degrees is required to meet the criterion for a mild ...

Many aspects of the physiology of the intervertebral disc (IVD) show clear diurnal rhythms. However, it is unknown whether IVD tissue contains functional circadian clocks and if so, how their ...

Background: Intervertebral disc degeneration (IDD) is widely regarded as the primary contributor to low back pain(LBP). As an immune-privileged organ, upon the onset of IDD, various components of the ...

Research shows that 90% of individuals will experience some form of back pain in their lives, and among these, many could prevent chronic pain through preventive spine care. Clinically, spine health ...

You have confirmed back pain with mild neurologic deficits. Now what? You have a discussion with the owner of your findings. You discuss how you suspect disc disease, as Dachshunds are the poster ...

Ophthalmologists and optometrists diagnose macular degeneration as part of a comprehensive eye exam. Accurate diagnosis is made through a combination of a clinical exam and specific tests. These can ...

The spine's critical functionalities include movement, stability, and protection of the spinal cord while common spinal conditions such as herniated discs, degenerative disc disease, spinal ...

Macular degeneration usually refers to the age-related degenerative changes in the retina that can result in loss of central vision. It is caused by abnormal blood vessel growth (a condition ...