The subsequent breakdown of the nuclear envelope terminates prophase and initiates prometaphase, during which the chromosomes become attached to and positioned on the mitotic spindle as it forms.

During this time the relative position of centrosomes within mitotic spindles did not change substantially. In embryos injected with anti-KLP61F antibodies, the movement of centrosomes in relation ...

This valuable study uses robust time-dependent microscopy assays to show that during HIV-1 infection, the viral accessory protein Vif causes cell cycle arrest during metaphase and not G2/M as ...

These drugs block mitosis, the process that cells use to divide and replicate. “By stopping this process, mitotic inhibitors prevent cancer cells from multiplying,” says Dr Shaikh. This can be ...

A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction.

A study shows how scientists can control cell division on demand outside of a living system. The work is a significant leap forward that can enhance our grasp of human biology and disease.

A living cell is a bustling metropolis, with countless molecules and proteins navigating crowded spaces in every direction.

The School of Neurobiology, Biochemistry & Biophysics, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel ...

Changes in either chromosome structure or number can occur during cell division. Each human has 46 chromosomes, 22 pairs of autosomes and 1 pair of sex chromosomes (XX: female or XY: male). During ...

On November 1, Shenzhen Chipscreen Biosciences Co., Ltd. (hereinafter referred to as 'Chipscreen Biosciences') and its wholly-owned subsidiary Chengdu Chipscreen Pharmaceutical Ltd., received the ...

MMS-I in patients with early-stage invasive melanoma had a less than 1% risk of local recurrence and disease-specific mortality.

The transcriptional regulation program is evaluating fadraciclib, a CDK2/9 inhibitor, and the anti-mitotic program plogosertib, a PLK1 inhibitor, in patients with both solid tumors and hematological ...