Liver-specific SMN1 gene therapy both improved liver functioning, and also reduced other SMA-like symptoms in a mouse model ...

Explore how E-selectin-targeted polymer-doxorubicin therapy induces regression in colorectal liver metastases.

Accumulation of extracellular matrix (ECM) in liver fibrosis is associated with changes in protein abundance and composition depending upon etiology of the underlying liver disease. Current efforts to ...

A New 3D Bioprinted Model Offers a Novel Tool to Study Common Liver Disease, and Perhaps Find an Effective Treatment Jan. 23, 2024 — Metabolic dysfunction--associated steatohepatitis or MASH ...

Conclusions Mouse models have significantly contributed to our understanding of liver fibrosis and its potential for regression. While no model perfectly replicates human disease, these experimental ...

Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, ...

Intestinal infections can change the composition of liver bile, leading to changes in immune function and gut bacteria, potentially helping fight off harmful bacteria .

Subset analysis of FASCINATE-2 Phase 2 trial demonstrated denifanstat improved fibrosis in difficult-to-treat MASH patientsBoth artificial ...

Since the adoption of a new model for assessing the severity of liver disease, women are more likely to be added to the waitlist for a liver transplant, more likely to receive a transplant ...