Additional experiments used GnT-IVa enzymes with different N-glycans capable of ... is the first case of a specific glycan self-regulating its own biosynthesis," said Kizuka.

Glycans are chains of sugars that attach to cells through proteins or lipids, changing their chemical characteristics.

The reversible attachment of an activated form of N-acetylglucosamine (UDP-GlcNAc) acts as a molecular switch between the growth and arrest of cells, establishing a new role for cell surface glycans.

Additional experiments used GnT-IVa enzymes with different N-glycans capable of binding the GnT-IVa lectin domain ... This is, to my knowledge, is the first case of a specific glycan self-regulating ...

mmu00510 N-Glycan biosynthesis - Mus musculus (mouse) path:mmu00511 Other glycan degradation - Mus musculus (mouse) path:mmu00512 Mucin type O-Glycan biosynthesis - Mus musculus (mouse) path:mmu00514 ...

In this study, researchers used high-performance liquid chromatography (HPLC) to characterize mucin O-glycans and food-derived N-glycans, focusing on their structural attributes and effects on A.

The N-glycans were isolated using a kit supplied by New England Biolabs (NEB, Ipswich, MA). Samples containing 20 µg mAb were first denatured using 1x denaturation buffer for 10 min at 100 °C. Then ...

Whether cholesterol biosynthesis can be adjusted to the availability of input carbon sources remains unclear. This study demonstrates that glutamine is directly sensed by and required for activation ...

State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu 214122, China School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China ...

Mechanistically, proteomic profiling and morphological characterizations revealed that AG-specific mAbs regulate AG biosynthesis, thereby inducing cell wall swelling. Thus, direct AG-binding by ...