COX-2 inhibition in TGRKO mice. (a) TGRKO mice treated with antibody to CD3ε and SC-236 (S; n = 7), NS-398 (N; n = 5) or vehicle (V; n = 8). P ≤ 0.05 for NS-398- or SC-236-treated mifepristone ...

摘要： 癌细胞对化疗药物的耐药性大大降低了癌症患者的治疗效果，化疗引起的毒副作用也严重影响了患者的生活质量。茶中主要活性成分表没食子儿茶素-3-没食子酸酯（EGCG）与顺铂、5-FU、多柔比星和紫杉醇的联合使用，增强了它们对肿瘤的增敏效果，并对抗了癌细胞的耐药性。这些效应似乎通过多种机制介导，包括对抗癌症干细胞介导的药物耐药性、增强药物敏感性、诱导细胞周期停滞和凋亡，以及阻断血管生成。此外，EGC ...

Firefighters in Nova Scotia are battling the largest wildfire in the Atlantic province's history. Officials say the fire on the southern tip of the province has burned about 20,000 hectares ...

Meloxicam is an enolcarboxamide with preferential COX-2 inhibitory activity. In vitro studies with human tissues have confirmed the high affinity of meloxicam for COX-2, whereas COX-1 was ...

WASHINGTON (AP) — The U.S. on Wednesday imposed sanctions on 398 firms across Russia, India, China and more than a dozen other nations, accusing them of providing products and services that ...

Power line technicians from Nova Scotia are on the ground in Tampa, Fla., assisting in power restoration after hurricanes Helene and Milton barrelled across the state, leaving extensive damage and ...

As global markets react to the recent U.S. election results, small-cap stocks have gained attention, with the Russell 2000 Index leading gains despite remaining below its record highs. In this dynamic ...

Moldovans voted Sunday in a tense presidential runoff that could decide whether the ex-Soviet country stays on a pro-European ...