Calcium channel blocker (CCB) (dihydropyridine). Nifedipine inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. The reduction in calcium influx causes ...
Nifedipine 30mg, 60mg, 90mg; ext-rel tabs. Aortic stenosis. Severe obstructive coronary artery disease. Avoid administration within 1–2 weeks post MI or in acute coronary syndrome. Heart failure.
A Coronary Disease Trial Investigating Outcome with Nifedipine gastrointestinal therapeutic system (ACTION) study was designed as a consequence of this discussion on calcium antagonists to ...