Given their non-migratory nature within the mineralized matrix, their unique dendrites are crucial for cell-to-cell communication in response to both intracellular and extracellular stimuli, such as ...

Bone development is the formation and growth of bones. New bone is formed by the action of specialised cells called osteoblasts and osteoclasts, either by directly laying down bone tissue into ...

In this study, our results uncover the function and mechanism of CHMP5 in the regulation of cell senescence and bone formation in osteogenic cells. Deletion of Chmp5 causes endolysosomal dysfunction ...

Studies have shown that inflammatory cell death leads to osteogenic cell pyroptosis and is the key to the development of osteoporosis. Various signals that induce inflammation in the body include ...

Department of Medical Life Sciences, Department of Medical Sciences (Graduate School), and Catholic Photomedicine Research Institute, College of Medicine, The Catholic University of Korea, 222 ...

Think back to that basic biology class you took in high school. You probably learned about organelles, those little 'organs' inside cells that form compartments with individual functions. For example, ...

You probably learned about organelles, those little “organs” inside cells that form compartments with individual functions. For example, mitochondria produce energy, lysosomes recycle waste ...

“This approach of utilizing metabolic modulation to improve MSC chondrogenic potential could be adapted into similar concepts for other therapeutic indications, such as osteogenic potential for bone ...

(2020). Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering ...