Previous laboratory and clinical studies showed that inhibiting the activation of the MAPK signaling pathway could attenuate acute lung injury.

38 Degrees is a community of more than a million people who – in a moment away from their busy days – take small actions on issues they care about, which all add up to something bigger, a movement for ...

Welcome to Taste Test, where every week our critic Jonah Flicker explores the most buzzworthy and interesting whiskeys in the world. Check back each Sunday for his latest whiskey review.

The final report by the joint parliamentary inquiry into the structural challenges in the audit, assurance and consultancy industry has been tabled with the committee, led by Labor senator Deborah ...

GDNF increased claudin-5 expression via the PI3K/AKT/FOXO1 and MAPK/ERK pathways. Meanwhile, GDNF promoted VE-cadherin expression by activating PI3K/AKT/ETS1 and MAPK/ERK/ETS1 signaling. The roles of ...

The crystal structure of the catalytic domain from the MAPK phosphatase Pyst1 (Pyst1–CD) has been determined at 2.35 Å. The structure adopts a protein tyrosine phosphatase (PTPase) fold with a ...

Western blot analysis was performed with the following antibodies: IRAK4 C-term (ab5985; Abcam), IRAK N-term (4363; Cell Signaling Technology), Flag (F3165; Sigma), IRAK1 (sc-7883; Santa Cruz), ...