The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME attempts to eliminate abnormal cells through immune ...

The TIME is a dynamic network composed of cancer cells, immune cells, and stromal components. During the early stages of tumorigenesis, the TIME ...

Hepatocellular carcinoma (HCC) is a significant global health issue, ranking as the sixth most prevalent malignancy and the ...

Additionally, miR-34a targets the PD-L1 gene. Overexpression of miR-34a following transfection for 48 hours suppressed PD-L1 mRNA expression, while Atractylodes macrocephala polysaccharide increased ...

Our central theme is to understand the immunological effects of extracellular vesicles (EVs). EVs are natural nanovesicles released from all cells and are present in all body fluids. We work both with ...

Meanwhile, as suggested by Parra et al., neoadjuvant chemotherapy exerted PD-L1 upregulation in NSCLC patients. It increased the density of CD68+ macrophages, which were associated with better ...

目前国内免疫药物主要有PD-1单抗和PD-L1单抗两大类。大家可能觉得，这两种药物其实是针对同一免疫通路的两个端点，机制上 ...

It is also being investigated in multiple phase 3 trials, whereby recent data showed that the drug slashed the risk of disease progression or death by 49% compared with Merck’s blockbuster drug ...

Extracellular vesicles (EV) are subcellular components derived from a cell that are essential mediators of intercellular communication. Exosomes are a type of extracellular vesicle secreted by the ...

Read more about our Product Review Guidelines here. The good news is if you have a face, you're a good candidate for topical exosomes. The not-so-great news? There aren't too many formulas on the ...

The Aethlon Hemopurifier has been designed to bind and remove these EVs from the bloodstream, which may improve therapeutic response rates to anti-PD-1 antibodies. In preclinical studies, the ...