AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central ...

10月16日，国际心脏研究学会官方杂志Journal of Molecular and Cellular Cardiology在线发表了中国科学院上海营养与健康研究所杨黄恬研究团队题为“Human embryonic stem cell-derived cardiovascular progenitor cells stimulate cardiomyocyte cell cycle ...

*仅供医学专业人士阅读参考ctDNA监测有望为晚期ER+乳腺癌治疗耐药后进展提供早期预警。过去十年中，晚期雌激素受体阳性（ER+）乳腺癌取得了重大进展[1]。内分泌治疗及细胞周期蛋白依赖性激酶4/6抑制剂（CDK4/6i）的发展和应用显著延长了患者无 ...

2024 年 11 月 6 日，我院 天然药物及仿生药物全国重点实验室 PI 崔一民教授团队与刘振明研究员团队合作在 Advanced Science 发表了最新研究成果 “Targeting SLITRK4 Restrains Proliferation and Liver Metastasis in Colorectal Cancer Via Regulating PI3K/AKT/ NFκB ...

The phosphatidylinositol 3-kinase (PI3K)-AKT signaling pathway is one of the most critical and extensively investigated signaling pathways. It is the central regulator of various cellular ...

Cancer remains one of the leading global causes of mortality, with an estimated increase in cases due to lifestyle, ...

Cancer remains one of the leading global causes of mortality, with an estimated increase in cases due to lifestyle, environmental, and genetic ...

Cancer is thought to be the second most prevalent and leading cause of mortality worldwide, affecting both men and women among other chronic diseases. While there are several treatment options ...

The company’s lead development candidate is Paxalisib, a small molecule, brain-penetrant inhibitor of the PI3K/AKT/mTOR pathway, which is developed as a potential therapy for glioblastoma.