This study presents an important finding on the involvement of a Caspase 3-dependent pathway in the elimination of synapses for retinogeniculate circuit refinement and eye-specific territory ...

Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years of experience in consumer-facing health and wellness content. A new survey found that over half of adults under ...

On one hand, it has been proposed that caspase-3 activity in dendrites can be locally confined by proteasomal degradation of cleaved caspase-3 (Erturk et al., DOI: 10.1523/JNEUROSCI.3121-13.2014 ). On ...

Pancreatic cancer has multiple risk factors. Some, like lifestyle choices, can be modified. Others, like genetics, race, and age, are beyond your control. Science has yet to uncover what triggers ...

a randomized Phase 3 trial of TH-302 in patients with advanced first-line pancreatic cancer is planned to be initiated together with our partner Merck KGaA. We are grateful to the clinical ...

40, Goettingen 37075, Germany; albrecht.neesse{at}med.uni-goettingen.de Objective Desmoplasia and hypovascularity are thought to impede drug delivery in pancreatic ductal adenocarcinoma (PDAC).

Pancreatic cancer is a type of cancer that begins in the tissues of the pancreas, an organ located behind the lower part of the stomach that produces enzymes to aid digestion and hormones like ...

Recent research from the University of Helsinki sheds new light on the behavior of the KRAS gene in two of the deadliest cancers—pancreatic and colorectal cancer. These findings suggest ...

The results displayed that Rapamycin increased the apoptosis rate and the expression of cleaved caspase-3, whereas Bafilomycin A1 and Chloroquine reduced the apoptosis and the expression of cleaved ...

More than 66,000 Americans will be diagnosed with pancreatic cancer this year. Learn more about the disease and how PanCAN can help.