Most organic drugs contain one acid group, usually a carboxylic acid, -COOH, or one basic primary, secondary, or tertiary amino group, NC 1-3, [3,22,27,28,29] that determines the acid-base ...

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Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

Background Normal tension glaucoma (NTG) is commonly treated with anti-glaucoma medications. Recently, selective laser trabeculoplasty (SLT) has been demonstrated to lower the intraocular pressure ...