Common causes include nickel, fragrances, rubber, and certain plants. Dyshidrotic dermatitis (or pompholyx eczema) causes itchy, watery blisters, usually on your palms and the sides of your fingers.

The course is frequently chronic. Dyshidrosis can develop into a debilitating disorder. Pompholyx is distinguished from dyshidrosis by a more acute and severe eruption of large bullae on the palms.

Dyshidrosis, sometimes called pompholyx or dyshidrotic eczema, is a common chronic dermatitis of the palms and soles that may lead to significant impairment of occupation and quality of life.