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自1990年代以来,研究人员发现了大量的lncRNA,并揭示了它们的调控作用,然而,对它们在人类疾病中的意义仍知之甚少,这项新研究提示我们 ...
该研究开发了一种基于CRISPR-Cas13的靶向RNA的转录组规模的CRISPR筛选技术,并使用该技术在来自不同组织的5种人类细胞中筛选鉴定了778个必需的lncRNA。
Long non-coding RNAs (lncRNAs) are often found to have important regulatory roles. Objective To assess the lncRNA expression profile of oesophageal squamous cell carcinoma (OSCC) and identify ...
Python script to quickly extract promoter and terminator regions with the NCBI API. Search for the presence of individual pattern or transcription factor responsive elements with manual sequence ...
π-FISH rainbow 检测了 HeLa 细胞中 lncRNA NEAT1、Pol II 蛋白和 MAPK15 基因组位点的空间分布,证明了该技术可以实现DNA、RNA 和蛋白质共同检测,这一突破对 ...