namely proteasomes and autophagy. The researchers led by Professor Seogang Hyun from Chung-Ang University, Korea, identified a drug that could preserve the performance of these systems ...

As such, there is an ongoing need for the identification of novel inhibitory receptors as drug targets. Most inhibitory receptors signal via immunoreceptor tyrosine-based inhibitory motifs (ITIMs) and ...

Consequently, there is a pressing need for new drugs, preferably with novel modes of action to avert the problem of cross-resistance. Several new targets have been proposed, including proteins ...

Proteomic research serves as a primary source for drug target identification. We employed proteome-wide Mendelian randomization (MR), genetic correlation analysis, and colocalization analysis to ...

In true Target fashion, the excitement doesn’t stop with just the products. Target is hosting in-store events and giveaways at select locations on launch day to celebrate The Cuddle Collab ...

In the final weeks of the race, male voters are among the biggest persuasive targets for the Harris campaign as it seeks to erode part of Trump’s advantage by spending tens of millions in TV ads ...

The Dublin gang that is now the primary target of the Irish element of the ... from Ballyfermot and is now the biggest gang selling drugs in the Republic and also the largest group importing ...

Israel launched extensive airstrikes against Hezbollah targets in Lebanon Thursday. The militant group’s leader said two days of attacks on its members amounted to a declaration of war.

Roula Khalaf, Editor of the FT, selects her favourite stories in this weekly newsletter. UK retail bellwether Next is planning to target wealthier shoppers as consumers increasingly buy “fewer ...

Puerto Plata.-Authorities from the Dominican Republic and the United States have conducted a series of raids to dismantle a major international drug trafficking network. Several individuals have been ...

The team proposed a new treatment strategy to target BCL2—a protein responsible for preventing cell death. A clinical trial for prostate cancer testing the BCL2 inhibitor venetoclax—a drug ...