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News Medical
13 小时
TRiC mutations found to cause developmental brain malformations in children
In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.
eLife
18 小时
Interplay of condensate material properties and chromatin heterogeneity governs nuclear ...
Nuclear condensates play many important roles in chromatin functions, but how cells regulate their nucleation and growth within the complex nuclear environment is not well understood. Here, we report ...
21 小时
Scientists synthesize unsymmetrical ureas using non-phosgene method
Unsymmetrical ureas can form multiple stable hydrogen bonds with proteins. Since drugs containing urea functional groups ...
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