With each breath, a human may inhale thousands of harmful microbes into the lungs. Mucus, the gel-like moist substance ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

Departments of Pharmacology, UT Southwestern Medical Center, Dallas, USA Departments of Peter O’Donnell Jr. Brain Institute and Psychiatry, UT Southwestern Medical Center, Dallas, USA Department of ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

We purified GST fusion proteins on glutathione agarose beads (20 μl) in buffer H (120 mM KOAc, 20 mM Tris-OAc, pH 7.9, 1 mM EDTA, 20% glycerol). Equal amounts of GST fusion proteins were used in ...

In summary, these BLI data demonstrate that B. subtilis MinD is capable of binding membrane in both monomeric and dimeric form, while the presence of ATP in the binding pocket appears to affect both ...