Proliferating cells, in particular tumor cells, are characterized by a high amount of the dimeric form of the pyruvate kinase isoenzyme type M2 (Tumor M2-PK). Tumor M2-PK can be determined in EDTA ...
About PYRUKYND® (mitapivat) PYRUKYND is a pyruvate kinase activator indicated for the treatment of hemolytic anemia in adults with pyruvate kinase (PK) deficiency in the United States, and for the ...
This study provides convincing evidence for functional subpopulations of β-cells responsible for Ca2+ signal initiation and maintenance using novel three-dimensional light sheet microscopy imaging and ...
Rocket Pharmaceuticals, Inc. , a fully integrated, late-stage biotechnology company advancing a sustainable pipeline of genetic therapies for rare disorders with high unmet need, today announced that ...
Meanwhile, there are a couple of orally-active pyruvate kinase R activators from Forma Therapeutics and Agios – etavopivat and mitapivat, respectively – in mid-stage development, and Pfizer ...
Mirae Asset Global Investments Co. Ltd. raised its position in Rocket Pharmaceuticals, Inc. (NASDAQ:RCKT – Free Report) by 21.5% during the third quarter, according to its most recent filing with the ...
The growing demand for alopecia treatments is mainly driven by the rising global prevalence of alopecia, influenced by various factors, as well as increasing research and development efforts in ...