and suggested that this compound may be an intermediate in the oxidation of pyruvic acid generally. If so, acetylphosphate should give an increased oxygen uptake with enzyme preparations which ...

(2) Sepsis is characterized by a failing starvation response resulting in impaired PDC activity and FFA oxidation, likely leading to decreased acetyl-CoA levels thereby inactivating PC. (3) ...

The cause of the climactic transition has been unclear. Now a research team from China finds evidence that atmospheric oxidation led to Mars being cold and bipolar in its early history.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mevalonate pathway produces essential ...

A high plasma lactate can be secondary to hypoxia, cardiac disease, infection, or convulsions, whereas primary lactic acidosis may be caused by disorders of pyruvate metabolism and respiratory chain ...

decreased lipid oxidation, decreased free fatty acid concentration, and increased peripheral insulin-related glucose uptake. [70] Treatment. The management of metformin overdose is primarily ...

pyruvate carboxylase deficiency; PA, propionic acidemia; THAN, transient hyperammonemia of the newborn; VLCADD, very long chain acyl-CoA dehydrogenase deficiency. Adapted with permission from ...

2006). Apart from glutamine metabolism, SIRT4 inhibits β-oxidation of fatty acids, unlike SIRT3 and SIRT5. Through deacetylation of malonyl-coA decarboxylase (MCD), SIRT4 suppresses and catalyzes the ...

Department of Microbiology & Cell Biology, Indian Institute of Science, India Centre of Infectious Disease Research, Indian Institute of Science, Bangalore, India Pharmacology Division, CSIR-Central ...

Pancreatic ductal adenocarcinoma (PDAC), the most common pancreatic cancer, is a deadly cancer, often diagnosed late and resistant to current therapies. PDAC patients are frequently affected by ...

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