Binding was determined using the chemiluminescence HRP method (Millipore, Billerica, MA, United States). Protein expressions of HMGB1, AQP1, RAGE, TLR4, NF-κB, and GAPDH were analyzed using ImageJ ...

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Two functional types of RAGE have been associated with neurological diseases: cell membrane-bound (full length) and soluble. In general, ligand binding to full-length RAGE initiates sustained ...

First, peripheral levels of RAGE ligands, such as S100/calgranulins, AGEs and HMGB1, can be reduced ... In general, ligand binding to RAGE initiates cellular activation and receptor-dependent ...

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SALT LAKE CITY (KUTV) — Dash camera from another driver captured video of the road rage incident that led to the death of a 50-year-old man in Salt Lake County. The incident happened after 5 a.m ...

We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the lands where we live, learn and work.

“Funny cuz Elon was the kid on the cover of Evil Empire,” the Rock & Roll Hall of Famer quipped, sharing the cover of Rage’s 1996 album, which features a clean-cut kid wearing a cape and a shirt ...