If the clinical history is not helpful (e.g., there is no documentation of the efficacy of drug "A ... a reactive renin system should have an increased renin while on ACE inhibitor therapy.

Drug-induced AKI (acute kidney injury) is common and may include medications not previously known to exhibit this safety signal.

Angiotensin II (AT-II)-Receptor Antagonists are Reviewed. Research focused on blocking the renin- angiotensin system (RAS) led to the discovery of angiotensin-converting-enzyme (ACE) inhibitors ...

Those living with alopecia areata would need to stay on the medication for the results to be maintained. Biologic Drugs vs. JAK Inhibitors Another class of drugs called biologics are also commonly ...

It is further recommended that current drugs be replaced with a more appropriate and less difficult ... commonly including a long-acting CCB, a renin-angiotensin system (RAS) blocker (an ACE inhibitor ...

Bristol-Myers Squibb has won FDA approval for the first LAG-3 inhibitor drug ahead of its rivals in cancer immunotherapy, including Merck & Co. The US regulator cleared BMS' LAG-3 drug relatlimab ...

The hope is that the two drugs could be combined with new KRAS inhibitor drugs from Amgen and Mirati to improve their efficacy, as well as potentially a dual therapy for other cancers. BridgeBio ...

Hyperuricemia (HU), characterized by elevated uric acid (UA) levels in the blood, is a global health concern associated with various conditions, including cardiovascular diseases, gout, hypertension, ...

If you take Cialis, there’s a chance of limb pain, whereas Viagra side effects, or other oral ED drugs, do not have this risk. Otherwise, Cialis and Viagra are both PDE5 inhibitors, so they work ...

You might just know someone, close or distant, who has struggled with drug addiction at one point in time. It could be a distant relative or someone you went to school with, but the sheer probability ...

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead ...

(Credit: WEHI) They discovered a critical insight: a hyperactive inflammatory pathway in the body that drives the disease’s progression. This led them to test JAK inhibitors — drugs already approved ...