The connection between the drugs and kidney problems has long been known, but how and why that happens has been a mystery ...

The class of drugs, known as renin–angiotensin system (RAS) inhibitors, block the effects of the renin enzyme, relaxing blood ...

High blood pressure, or hypertension, affects nearly half of all Americans, and many are unaware they have it. This condition ...

Scientists have discovered how long-term treatment of high blood pressure with commonly prescribed drugs can destroy the kidney's ability to filter and purify blood. The finding could open the door to ...

A new study by researchers at the University of Virginia (UVA) School of Medicine has uncovered how prolonged use of renin-angiotensin system (RAS) inhibitors – commonly prescribed for high blood ...

New drugs in development Many new protease inhibitors ... SPP635 entered Phase I trials in October 2005. The third group of renin inhibitors from Speedel was developed in collaboration with ...

Monitor for hyperkalemia with drugs that inhibit the renin-angiotensin-aldosterone sytem (eg, ACE inhibitors, ARBs, spironolactone, eplerenone, aliskiren), or NSAIDs. Anticholinergics, other ...