In particular, the ratio of ATP production to oxygen consumption (P/O) is considered integral and constant in all discussions of oxidative phosphorylation. This view is maintained despite the fact ...

Its synthesis, which occurs in the mitochondria, through oxidative phosphorylation (OXPHOS) is a complex, multi-step process. When one or more of the elements of this process malfunction ...

In mammals, pyruvate is the primary substrate for lactate production. It plays a critical role in metabolism by linking glycolysis, where it is produced, with the mitochondrial oxidative ...

Mitochondria: Small organelles within cells that serve as the cell’s powerhouse, generating ATP through oxidative phosphorylation (OXPHOS) and cellular respiration. EGFR (Epidermal Growth Factor ...

which is a cornerstone of energy production in cellular respiration. In its reduced form, NADH, the molecule seems to participate in the production of ATP through oxidative phosphorylation ...

Notably, we found that PA28γ can enhance C1QBP protein stability in OSCC. Functionally, PA28γ contributes to the malignant progression of OSCC by affecting mitochondrial morphology and oxidative ...

Over two decades ago, increased levels of RNA oxidation were reported in postmortem patients with ALS, Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. Interestingly, not all cell types ...

It also commonly occurs as a person approaches the end of life. Diagnosing Cheyne-Stokes respiration can be difficult because it often occurs while you are asleep. The presence of Cheyne-Stokes ...

McGowan Institute for Regenerative Medicine, Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15219, United States ...