Spironolactone is a generic drug prescribed for certain conditions, such as high blood pressure in adults. As with other drugs, spironolactone can cause side effects, such as dizziness and high ...

The CLEAR SYNERGY trial found that spironolactone may reduce the risk of new or worsening heart failure; however, it did not significantly impact the rate of death, new heart attack or stroke.

The routine administration of spironolactone to patients after a myocardial infarction (MI) did not reduce either of the coprimary outcomes in the CLEAR SYNERGY (OASIS 9) trial. However ...

Among 203 patients, 71% of those taking SZC achieved the primary endpoint of optimal response -- normokalemia while on at least a 25-mg dose of spironolactone daily without rescue therapy for ...

Get detailed information on Furosemide and Spironolactone, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it.

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The CLEAR SYNERGY trial found that spironolactone may reduce the risk of new or worsening heart failure; however, it did not significantly impact the rate of death, new heart attack or stroke. More ...

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Sodium zirconium cyclosilicate (SZC) helped to optimize spironolactone use in patients with heart failure and reduced ejection fraction (HFrEF) and hyperkalemia, based on findings from the REALIZE-K ...

However, spironolactone is associated with serious adverse events, including hyperkalemia and gynecomastia. [10,11] Consequently, clinical benefits related to the use of spironolactone are ...