Levothyroxine therapy was not associated with differences in cognitive decline among women with vs without hypothyroidism across menopause.

The hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian endocrine system. The anterior pituitary gland synthesizes and secretes multiple ...

They conclude that reduction in TSH bioactivity in the absence of TRH and the aberrant response to hypothyroidism of double-knockout mice point to a dominant role for TRH in thyroid hormone ...

Three principal thyroid autoantigens are involved in AITD. These are thyroperoxidase (TPO), thyroglobulin (Tg) and the TSH receptor. Other autoantigens, such as the Sodium Iodide Symporter (NIS ...

Methods: Triiodothyronine (T3), thyroxine (T4), thyroid stimulating hormone (TSH), and leptin were measured in 118 obese children (aged 4.5–16 years); thyroid function was also determined in 107 ...

This approach works, however, only if the hypothalamic-pituitary-thyroid axis is normal. Conversely, the strategy of first-line TSH measurement can miss patients with CH. In this Review ...

Poland: A recent study published in The Journal of Clinical Pharmacology revealed that subclinical hyperthyroidism may amplify the gonadotropin-lowering effects of metformin in ...