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生物谷
15 天
Nature:中国科学家揭示机体T细胞分化背后的特殊分子机制
通过结合多种基因和细胞生物学技术,研究人员利用临床前模型进行研究后表明,神经肽受体RAMP3在T细胞发育过程中或许发挥着重要作用;被神经肽和其受体所影响的神经免疫回路在决定T细胞命运方面发挥着关键角色,研究人员还深入剖析了神经肽如何确保最佳的T细胞分化并驱动强大的抗病毒反应。研究者认为,神经免疫回路的改变或许有助于平衡不同类型的T细胞并产生更好的免疫反应,比如,此前研究结果表明,TH2分化超过TH ...
Medical Xpress
18 天
Uncovering the mechanisms behind T cell differentiation
When activated in response to environmental stimuli, these cells can differentiate into either TH1 cells, which fight against viruses and intracellular pathogens, or TH2 cells, which fight against ...
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