To differentiate into T cells, immature thymocytes must engage, through their antigen-specific T-cell receptor, peptides derived from self proteins presented by cortical epithelial cells in the ...

In fact, we found that the incidence of diabetes in nonobese diabetic mice could be diminished considerably by increasing the negative selection of insulin-specific thymocytes through ...

The differentiation of T cells in the thymus is dependent on the interactions between the thymocytes and the cells ...

The treatment of thrombosis as well as the prevention of recurrent thrombosis in APS has been focused on utilizing antithrombotic medications. Recurrences, in spite of treatment, have been ...

An ASA is defined as an immunoglobulin with antibody activity against a sperm antigen that plays a role in fertility, since not every antibody that binds to the sperm surface influences sperm ...

Siplizumab is under clinical development by ITB-Med and currently in Phase I for Amyotrophic Lateral Sclerosis.