Mice injected in the thymus with procainamide-hydroxylamine, a metabolite of procainamide, develop autoimmune features resembling drug-induced lupus. Here, we show that when thymocytes undergo ...

Flow cytometric analysis. The lymphocyte composition of lymphoid organs was determined following triple staining with antibodies against CD4, CD8, and B220. Effector/memory CD4+ T cells were ...

该研究揭示，ME2缺失可阻断CD8+T细胞的三羧酸（TCA）循环，导致中间代谢产物富马酸（fumarate）在细胞内堆积。 从治疗干预的角度来说，要想帮CD8 + T ...

The in vivo data showed that when the thymus organoid was injected into a SCID mouse, it gave rise to fully mature T cells that express a TCR and differentiate into CD4 or CD8 T cells. In addition ...

Researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne have discovered new cells that drive the aging process in the thymus that could unlock a way to restore ...

In the classification system of the World Health Organization (WHO), this is stage 1 (asymptomatic). In the slightly different system of the CDC, it is also described as stage 1 (but defined in terms ...

MA Farage and KW Miller are employees of Proctor and Gamble. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in ...

£35 means we can empower more people living with HIV to challenge stigma with our information workshops, videos and broadcasts. Most HIV-negative adults have between 500 and 1500 CD4 cells in a cubic ...

Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...