Flow cytometric analysis. The lymphocyte composition of lymphoid organs was determined following triple staining with antibodies against CD4, CD8, and B220. Effector/memory CD4+ T cells were ...

The hematopoietic stem cells (HSC) reach the thymus from the bone marrow where they become early thymic progenitors (ETP). At this stage several differentiation steps take place starting with the ...

该研究揭示，ME2缺失可阻断CD8+T细胞的三羧酸（TCA）循环，导致中间代谢产物富马酸（fumarate）在细胞内堆积。 从治疗干预的角度来说，要想帮CD8 + T ...

Thymus vulgaris (thyme) is an herb known for flavoring food, but it's also believed to have medicinal properties. Research shows that it may have anti-inflammatory, antimicrobial, antioxidant, and ...

Mechanisms whereby a rapid increase in CD4+T-cells may mediate the development of T1DM in ART-treated PLWH ... it is essential to understand the integrity of the thymus in PLWH who develop T1DM after ...

AL de Araújo and LCR Silva received fellowship grants from CAPES and FAPESP (#2011/18268-4). G Benard and JR Fernandes received grants from CNPq and FAPESP (#2011/08817-0). The authors have no ...

Researchers at the Walter and Eliza Hall Institute of Medical Research (WEHI) in Melbourne have discovered new cells that drive the aging process in the thymus that could unlock a way to restore ...

The in vivo data showed that when the thymus organoid was injected into a SCID mouse, it gave rise to fully mature T cells that express a TCR and differentiate into CD4 or CD8 T cells. In addition ...

(b) Southern blot analysis of heart (H), thymus (T), kidney (K ... (lane 1), GR expression vector (lane 2) or purified CD4+ or CD8+ thymocytes from control (Con) or TGRKO (KO) mice.