Toll-like receptors (TLRs) and their signalling pathways have therapeutic potential for the treatment of inflammation, cancer, infection, allergy and autoimmunity. The elucidation of the structure ...
Toll-like receptors (TLRs) recognise pathogen-associated molecular patterns (PAMPs) to detect the presence of pathogens. In addition to their role in innate immunity, TLRs also play a major role in ...
Recent studies have demonstrated that Toll-like receptors (TLRs), particularly those recognizing immune complexes containing DNA and RNA, contribute to Th cell activation in various autoimmune ...
Division of Immunology, Infection and Inflammation, University of Glasgow, Glasgow, UK Correspondence to: F Y Liew Division of Immunology, Infection and Inflammation, University of Glasgow, Glasgow ...
lumc.nl Objective Mast cells may play a role in rheumatoid arthritis (RA), but activation of human mast cells in autoimmune settings has been little studied. Toll-like receptors (TLR) and Fcγ ...
The second volume of our Community Series on “The Role of Toll-like Receptors and their Related Signaling Pathways in Viral Infection and Inflammation” delves into the intricate mechanisms through ...
Encouraging Preclinical Data: Decoy20 has produced efficacy in preclinical studies across a variety of tumor types and in combination with four different classes of existing drugs, demonstrating both ...