Naldemedine is efficacious for preventing opioid-induced constipation and for improving QOL among individuals with cancer.

Stomachaches and pains can occur for various reasons, including constipation, gas, and heartburn. In some cases, ...

Researchers at University of Tsukuba revealed that administering naldemedine, which is a constipation medication, alongside opioids effectively prevents opioid-induced constipation, thereby improving ...

After 14 days of treatment, 64.6% of the patients taking ... More information: Jun Hamano et al, Naldemedine for Opioid-Induced Constipation in Patients With Cancer: A Multicenter, Double-Blind ...

Along with cancer treatment comes pain which has often been treated with opioids. However, these opioids have some adverse effects such as constipation which can diminish one’s quality of life (QOL).

In a randomized manufacturer-sponsored study, the peripheral opioid antagonist methylnaltrexone was investigated as therapy for opioid-induced constipation ... promise for treatment of one of ...

This condition, also known as opioid-induced constipation, is prevalent and frequently does not resolve on its own ... one receiving naldemedine and the other a placebo. After 14 days of treatment, 64 ...

Impact of Adjuvant Chemotherapy on Resected Intraductal Papillary Mucinous Neoplasm-Derived Pancreatic Cancer: Results From an International Multicenter Study Preventive use of naldemedine for ...

or placebo group in a 1:1 ratio for 14 days with protocol treatment. The primary end point was the proportion of patients with a Bowel Function Index (BFI) of <28.8 on day 14. The secondary end points ...

Medical management of opioid-induced constipation differs from other forms of condition Oct 17, 2018 Pelvic Floor Society statement—use of mesh surgeries for constipation and rectal prolapse ...